CHADDS FORD, Pa., Feb. 3, 2012 /PRNewswire/ — Endo Pharmaceuticals Holdings (Nasdaq: ENDP – News) will announce its fourth quarter and full year 2011 financial results on February 24, 2012 and will host a conference …
17-01-2012 09:32 “Acute High-Dose Intravenous Epoetin Does Not Increase Blood Pressure in Critically Ill Patients with Acute Kidney Injury” with Zoltan H. Endre, MD, University of Otego Christchurch, New Zealand. bit.ly
( NYU Langone Medical Center / New York University School of Medicine ) A new study by NYU Langone Medical Center and Northwestern University Feinberg School of Medicine shows novel PSA velocity risk count testing may provide a more effective way for physicians to screen men for clinically significant prostate cancer. The new study, published online by the British Journal of Urology …
Editor's Choice Academic Journal Main Category: Urology / Nephrology Article Date: 02 Feb 2012 – 10:00 PST
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Patient / Public: Healthcare Prof: A study by Wake Forest Baptist Medical Center reveals that the cause for bedwetting is often constipation, and not always bladder problems. If left undiagnosed, bedwetting can be an unnecessarily long, expensive and difficult challenge to cure. The study is published online in the journal Urology.
The association between excess stool in the rectum (the lower 5-6 inches of the intestine) and bedwetting was first reported in 1986. The study involved 30 children aged between 5 to 15 years, old who sought treatment for bedwetting. The researchers found that although the majority had normal bowel habits, all 30 children has excess stool in their rectums. After laxative therapy, 83% (25 children) were cured of bedwetting within 3 months.
Lead researcher Steve J. Hodges, M.D., assistant professor of urology at Wake Forest Baptist, explained:
“Having too much stool in the rectum reduces bladder capacity. Our study showed that a large percentage of these children were cured of nighttime wetting after laxative therapy.
Parents try all sorts of things to treat bedwetting – from alarms to restricting liquids. In many children, the reason they don't work is that constipation is the problem.”
According to Hodges, although the association was first reported in 1986, the finding did not result in a significant change in clinical practice, maybe because the definition of constipation is not standardized or uniformly understood by all physicians and lay people.
Hodges, explained:
“The definition for constipation is confusing and children and their parents often aren't aware the child is constipated. In our study, X-rays revealed that all the children had excess stool in their rectums that could interfere with normal bladder function. However, only three of the children described bowel habits consistent with constipation.”
Current guidelines of the International Children's Continence Society advise asking children and their patents if the consistency of the child's stool is hard, and if their bowel movements occur irregularly (less often than every other day).
Hodges, said:
“These questions focus on functional constipation and cannot help identify children with rectums that are enlarged and interfering with bladder capacity. The kind of constipation associated with bedwetting occurs when children put off going to the bathroom. This causes stool to back up and their bowels to never be fully emptied. We believe that treating this condition can cure bedwetting.”
Study participants were first treated with polyethylene glycol (Miralax®) to clean out their bowel. Miralax works by causing the stool to retain water, thus softening it. Stimulate laxatives or enemas were used in children whose rectums remained enlarged after initial bowel clean out.
Hodges warned that any medical treatment for bedwetting should be supervised by a physician.
In order to identify children with excess stool in their rectums, the researched used abdominal X-rays. A special diagnostic method that involves measuring rectal size on the X-ray was developed by Hodges and radiologists at Wake Forest Baptist. Hodges explained that rectal ultrasound is another method that can be used for diagnosis.
Hodges, explained:
“The importance of diagnosing this condition cannot be overstated. When it is missed, children may be subjected to unnecessary surgery and the side effects of medications. We challenge physicians considering medications or surgery as a treatment for bedwetting to obtain an X-ray or ultrasound first.”
The researchers warned that some cases in their study may have improved on their own over time. They explain, in order to test the treatments success more accurately and identify true response from cases that would resolve over time, constipated children should be randomly assigned to receive either laxative therapy or an inactive therapy.
Hodges' co-author on the study is Evelyn Y. Anthony, MD, a radiologist at Wake Forest Baptist.
Written by Grace Rattue Copyright: Medical News Today Not to be reproduced without permission of Medical News Today
Visit our urology / nephrology section for the latest news on this subject. Urology
Source: Wake Forest Baptist Medical Center
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(MedPage Today) — SAN FRANCISCO — Prostate cancer that has already spread to other organs at time of diagnosis is left untreated in 11% of cases, and demographics make a difference in the decision, researchers reported.Source: http://www.medpagetoday.com/rss/Urology.xml
(MedPage Today) — A look at why some stockbrokers are successful, a study that brings oncologists’ worst nightmare to life, and a timely Eureka moment in the war against parasites highlight this week’s collection of Lab Notes.Source: http://www.medpagetoday.com/rss/Urology.xml
(MedPage Today) — Another large study has confirmed that cancer survivors have better physical function and quality of life when they are physically active after their treatment ends, researchers found.Source: http://www.medpagetoday.com/rss/Urology.xml
SAN FRANCISCO (MedPage Today) — Regular vigorous exercise tones down tumor promoter genes and up regulates tumor suppressor genes for men with prostate cancer, researchers found.Source: http://www.medpagetoday.com/rss/Urology.xml
SAN FRANCISCO (MedPage Today) — External beam radiation is the most toxic and expensive among common prostate cancer treatments over the long-term, a national registry study suggested.Source: http://www.medpagetoday.com/rss/Urology.xml
SAN FRANCISCO (MedPage Today) — For localized prostate cancer, proton beam radiation offers no advantage in minimizing recurrences or side effects, study results suggested.Source: http://www.medpagetoday.com/rss/Urology.xml
NATICK, Mass., Feb. 2, 2012 /PRNewswire/ — Boston Scientific Corporation (NYSE: BSX – News) announces financial results for the fourth quarter and full year ended December 31, 2011, as well as sales and earnings …
SAN FRANCISCO (MedPage Today) — A novel drug that emits bone metastasis-targeted radiation cuts down on skeletal-related events in castration-resistant prostate cancer patients, researchers found.Source: http://www.medpagetoday.com/rss/Urology.xml
SAN FRANCISCO (MedPage Today) — An investigational androgen receptor antagonist substantially boosts survival in castration-resistant prostate cancer, phase III trial results showed.Source: http://www.medpagetoday.com/rss/Urology.xml
Vision-Sciences, Inc. , a leading provider of unique flexible endoscopic products utilizing its proprietary sterile disposable EndoSheath® technology, today reported
TUESDAY, Jan. 31 (HealthDay News) — Vigorous exercise causes changes in some 180 prostate genes among men with early stage prostate cancer, a new study suggests.
Editor's Choice Main Category: Genetics Also Included In: Urology / Nephrology Article Date: 30 Jan 2012 – 10:00 PST
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Patient / Public: Healthcare Prof: Researchers at Geisinger Health System have found that genetic abnormalities may be the cause for the majority of cerebral palsy (CP) cases, a group of disorders that can involve the brain and nervous system functions, such as seeing, movement, hearing, thinking, and learning, rather than a difficult birth or other perinatal factors. CP is the most prevalent physical disability of childhood. The study is published in The Lancet Neurology.
According to the researchers, CP may be caused by several genetic factors, similar to other neurodevelopmental disorders, such as intellectual disability and autism. The study suggests children present with CP and CP-like conditions should be considered for genetic testing by their physicians.
Andres Moreno De Luca, M.D., research scientist at the Genomic Medicine Institute, Geisinger Health System, and lead research of the study, explained:
“There is a widespread misconception that most cases of CP are caused by difficult delivery leading to birth asphyxia. What we're finding is a growing body of evidence that suggests mutations in multiple genes are responsible for CP. In fact, we suspect these genetic abnormalities may also be the cause of some difficult births to begin with.”
Although there has been considerable improvements in neonatal and obstetric care for over 4 decades, the global prevalence of GP has remained stable at 2-3 per 1,000 live births. Birth asphyxia (insufficient oxygen supply to fetuses), continues to be the most researched factor linked to CP – electronic fetal monitoring and other technologies have been created to identify fetal distress.
David Ledbetter, Ph.D., chief scientific officer, Geisinger Health System, said:
“What we're finding is the even though more preventative efforts have been put in place like fetal monitoring, the incidence of CP has not decreased. We've seen a five-fold increase in the rate of caesarean sections, which are doing in part to avoid potentially difficult delivery, and again, the CP rates remain steady. These findings lead us to believe genetics play a much bigger role than previously thought.”
According to the researchers, although the majority of CP cases are not due to birth asphyxia and CP, cases that are usually cannot be avoided by obstetric intervention, an estimated 76% of U.S. obstetricians faced medical malpractice litigation between 1999 and 2003, primarily for alleged birth mismanagement resulting in CP.
Dr. Luca explains:
“We now know of six genes that can cause CP when disrupted, and we estimate that many other developmental brain genes probably contribute to the genetic heterogeneity of this disorder. Many capable obstetricians face legal action even though research is telling us genetics is the likely cause of most cases of CP.”
According to the researchers, there will probably be an increase in research efforts, a change in the diagnostic approach, and eventually novel therapies for treating CP as more clinicians, researchers and the general population start to consider CP as a group of neurogenetic disorders.
Written By Grace Rattue Copyright: Medical News Today Not to be reproduced without permission of Medical News Today
Visit our genetics section for the latest news on this subject. Genomic insights into the causes and classification of the cerebral palsies Dr Andres Moreno-De-Luca MD, David H Ledbetter PhD and Christa L Martin PhD The Lancet Neurology. doi:10.1016/S1474-4422(11)70287-3. Jan 2012 Please use one of the following formats to cite this article in your essay, paper or report:
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PARSIPPANY, N.J., Jan. 30, 2012 /PRNewswire/ – Watson Pharmaceuticals, Inc. (NYSE: WPI – News), a leading specialty pharmaceutical company, announced today that the Company intends to release its fourth quarter …
NEW YORK, Jan. 30, 2012 /PRNewswire/ — Patients undergoing robotic prostatectomy surgery for the treatment of prostate cancer are more optimistic than those who choose traditional surgery for the removal …
The American Urological Association (AUA) today
announced that submissions are now being accepted for the
6th Annual Excellence in Urology Health Reporting
Awards, designed to recognize outstanding news coverage of
urologic disease topics. Presentation of the awards will
take place during the AUA Annual Scientific Meeting in
Atlanta, GA, in May.
The award is designed to honor journalists in both
trade and consumer media outlets for responsible,
informative reporting on health topics in urology. Awards
are given annually in the following categories: Consumer
Print Publications, Consumer Electronic Publications and
Trade Publications. Applicants may submit their own work,
or be nominated. Awardees will receive an honorarium and
award.
Submissions for the 2011 awards will be accepted through
Friday, March 16, 2012. All
materials must have been published or broadcast between
January 1, 2011 and December 31, 2011. All
submissions should include a cover letter, contact
information for both the nominee and submitter (if
applicable), and five copies (for electronic media, please
submit individual CD-ROMS; for print media, please limit to
8.5×11 format) of the submission.
All entries will be judged by a committee of urologists on
accuracy, completeness and public impact. Awardees will be
contacted by the end of March both by telephone and letter.
Decisions of the committee are final.
Press registration for the Annual Meeting will begin in
February 2012.
(MedPage Today) — Treatment of high-grade prostate cancer with brachytherapy significantly reduced prostate cancer-specific mortality compared with external beam radiation alone, results of a large study showed.Source: http://www.medpagetoday.com/rss/Urology.xml