Archive for Urology News

Abbreviated Radiotherapy Shows Promise in Prostate Ca

SAN FRANCISCO (MedPage Today) — Dramatically condensing radiation treatment for early prostate cancer into just five fractions produces good results without much toxicity, an early-phase study suggested.Source:
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Bone Drug Slows Mets in Aggressive Prostate Ca

(MedPage Today) — SAN FRANCISCO — Denosumab (Xgeva) delays onset of bone metastases for even the highest risk prostate cancer patients, researchers found.Source:
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Vaccine Eyed for Early-Stage Prostate Ca

SAN FRANCISCO (MedPage Today) — The immunotherapy agent sipuleucel-T (Provenge) appears safe for use earlier in prostate cancer, researchers found.Source:
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CKD Stage 3 Patients Benefit from Extended-Release Niacin – Video


13-01-2012 09:23 Andrew G. Bostom, MD, speaks about extended-release niacin/laropiprant and serum phosphorus levels in dyslipidemic patients who have stage 3 chronic kidney disease. bit.ly

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CKD Stage 3 Patients Benefit from Extended-Release Niacin – Video

Sleep Troubles May Up Prostate Cancer Risk

SAN FRANCISCO (MedPage Today) — Severe sleep problems suggestive of insomnia are associated with an increased risk of prostate cancer among older men, researchers found.Source:
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High FGF-23 in AKI Patients Predicts Worse Outcomes – Video


17-01-2012 09:25 “Fibroblast Growth Factor 23 as a Biomarker in Acute Kidney Injury” with Dr. Leaf. bit.ly

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High FGF-23 in AKI Patients Predicts Worse Outcomes – Video

Response to ESAs Predicts ESRD Risk – Video


17-01-2012 09:18 “Responsiveness to Erythropoiesis Stimulating Agents (ESA-R) Predicts ESRD in Non Dialysis CKD Patients” with Roberto Minutolo, MD, Second University of Naples, Italy. bit.ly

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Response to ESAs Predicts ESRD Risk – Video

Predictors of Hospitalizations in Maintenance Hemodialysis (HD) Patients – Video


17-01-2012 09:31 “Predictors of Hospitalizations in Maintenance Hemodialysis (HD) Patients” with Jochen G. Raimann, MD, Renal Research Institute and Beth Israel Medical Center, New York. bit.ly

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Predictors of Hospitalizations in Maintenance Hemodialysis (HD) Patients – Video

Endo Pharmaceuticals to Announce Fourth Quarter and Full Year 2011 Financial Results on February 24, 2012

CHADDS FORD, Pa., Feb. 3, 2012 /PRNewswire/ — Endo Pharmaceuticals Holdings (Nasdaq: ENDP – News) will announce its fourth quarter and full year 2011 financial results on February 24, 2012 and will host a conference …

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Endo Pharmaceuticals to Announce Fourth Quarter and Full Year 2011 Financial Results on February 24, 2012

BP Rises with ESAs Not Relate to Vasoconstriction – Video


17-01-2012 09:32 “Acute High-Dose Intravenous Epoetin Does Not Increase Blood Pressure in Critically Ill Patients with Acute Kidney Injury” with Zoltan H. Endre, MD, University of Otego Christchurch, New Zealand. bit.ly

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BP Rises with ESAs Not Relate to Vasoconstriction – Video

A new screening method for prostate cancer

( NYU Langone Medical Center / New York University School of Medicine ) A new study by NYU Langone Medical Center and Northwestern University Feinberg School of Medicine shows novel PSA velocity risk count testing may provide a more effective way for physicians to screen men for clinically significant prostate cancer. The new study, published online by the British Journal of Urology …

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A new screening method for prostate cancer

Bedwetting Linked To Constipation In Children

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Main Category: Urology / Nephrology
Article Date: 02 Feb 2012 – 10:00 PST

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A study by Wake Forest Baptist Medical Center reveals that the cause for bedwetting is often constipation, and not always bladder problems. If left undiagnosed, bedwetting can be an unnecessarily long, expensive and difficult challenge to cure. The study is published online in the journal Urology.

The association between excess stool in the rectum (the lower 5-6 inches of the intestine) and bedwetting was first reported in 1986. The study involved 30 children aged between 5 to 15 years, old who sought treatment for bedwetting. The researchers found that although the majority had normal bowel habits, all 30 children has excess stool in their rectums. After laxative therapy, 83% (25 children) were cured of bedwetting within 3 months.

Lead researcher Steve J. Hodges, M.D., assistant professor of urology at Wake Forest Baptist, explained:

“Having too much stool in the rectum reduces bladder capacity. Our study showed that a large percentage of these children were cured of nighttime wetting after laxative therapy.

Parents try all sorts of things to treat bedwetting – from alarms to restricting liquids. In many children, the reason they don't work is that constipation is the problem.”

According to Hodges, although the association was first reported in 1986, the finding did not result in a significant change in clinical practice, maybe because the definition of constipation is not standardized or uniformly understood by all physicians and lay people.

Hodges, explained:

“The definition for constipation is confusing and children and their parents often aren't aware the child is constipated. In our study, X-rays revealed that all the children had excess stool in their rectums that could interfere with normal bladder function. However, only three of the children described bowel habits consistent with constipation.”

Current guidelines of the International Children's Continence Society advise asking children and their patents if the consistency of the child's stool is hard, and if their bowel movements occur irregularly (less often than every other day).

Hodges, said:

“These questions focus on functional constipation and cannot help identify children with rectums that are enlarged and interfering with bladder capacity. The kind of constipation associated with bedwetting occurs when children put off going to the bathroom. This causes stool to back up and their bowels to never be fully emptied. We believe that treating this condition can cure bedwetting.”

Study participants were first treated with polyethylene glycol (Miralax®) to clean out their bowel. Miralax works by causing the stool to retain water, thus softening it. Stimulate laxatives or enemas were used in children whose rectums remained enlarged after initial bowel clean out.

Hodges warned that any medical treatment for bedwetting should be supervised by a physician.

In order to identify children with excess stool in their rectums, the researched used abdominal X-rays. A special diagnostic method that involves measuring rectal size on the X-ray was developed by Hodges and radiologists at Wake Forest Baptist. Hodges explained that rectal ultrasound is another method that can be used for diagnosis.

Hodges, explained:

“The importance of diagnosing this condition cannot be overstated. When it is missed, children may be subjected to unnecessary surgery and the side effects of medications. We challenge physicians considering medications or surgery as a treatment for bedwetting to obtain an X-ray or ultrasound first.”

The researchers warned that some cases in their study may have improved on their own over time. They explain, in order to test the treatments success more accurately and identify true response from cases that would resolve over time, constipated children should be randomly assigned to receive either laxative therapy or an inactive therapy.

Hodges' co-author on the study is Evelyn Y. Anthony, MD, a radiologist at Wake Forest Baptist.

Written by Grace Rattue
Copyright: Medical News Today
Not to be reproduced without permission of Medical News Today

Visit our urology / nephrology section for the latest news on this subject. Urology

Source: Wake Forest Baptist Medical Center

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Bedwetting Linked To Constipation In Children

Metastatic Prostate Cancer Often Untreated

(MedPage Today) — SAN FRANCISCO — Prostate cancer that has already spread to other organs at time of diagnosis is left untreated in 11% of cases, and demographics make a difference in the decision, researchers reported.Source:
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Lab Notes: Wall Street Success Genetic

(MedPage Today) — A look at why some stockbrokers are successful, a study that brings oncologists’ worst nightmare to life, and a timely Eureka moment in the war against parasites highlight this week’s collection of Lab Notes.Source:
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Cancer Survivors Do Better With Exercise (CME/CE)

(MedPage Today) — Another large study has confirmed that cancer survivors have better physical function and quality of life when they are physically active after their treatment ends, researchers found.Source:
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Workouts Shape Up Genes, Prognosis in Prostate Ca (with audio)

SAN FRANCISCO (MedPage Today) — Regular vigorous exercise tones down tumor promoter genes and up regulates tumor suppressor genes for men with prostate cancer, researchers found.Source:
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Most Common Tx for Prostate Ca Not Best Value

SAN FRANCISCO (MedPage Today) — External beam radiation is the most toxic and expensive among common prostate cancer treatments over the long-term, a national registry study suggested.Source:
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Proton Beam No Better than IMRT for Prostate Cancer (CME/CE)

SAN FRANCISCO (MedPage Today) — For localized prostate cancer, proton beam radiation offers no advantage in minimizing recurrences or side effects, study results suggested.Source:
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Boston Scientific Announces Results for Fourth Quarter and Full Year Ended December 31, 2011

NATICK, Mass., Feb. 2, 2012 /PRNewswire/ — Boston Scientific Corporation (NYSE: BSX – News) announces financial results for the fourth quarter and full year ended December 31, 2011, as well as sales and earnings …

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Boston Scientific Announces Results for Fourth Quarter and Full Year Ended December 31, 2011

Risk-Reward Balances for Endo Pharma

We are maintaining our Neutral stance on Endo Pharmaceuticals (NasdaqGS:ENDP – News) with a target price of $39.00.

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Risk-Reward Balances for Endo Pharma

Prostate Cancer Bone Mets Target of New Agent (with audio)

SAN FRANCISCO (MedPage Today) — A novel drug that emits bone metastasis-targeted radiation cuts down on skeletal-related events in castration-resistant prostate cancer patients, researchers found.Source:
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Bard Tops in 4Q, Charges Crimp Net

C.R. Bard's fourth quarter revenues and earnings beat the Zacks Consensus Estimates but profit dips on hefty charges.

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Bard Tops in 4Q, Charges Crimp Net

Novel Androgen Drug Gets ‘Wow’ in Advanced Prostate Cancer (CME/CE)

SAN FRANCISCO (MedPage Today) — An investigational androgen receptor antagonist substantially boosts survival in castration-resistant prostate cancer, phase III trial results showed.Source:
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Vision-Sciences Reports Record Third Quarter Fiscal 2012 Net Sales of $4.3 Million

Vision-Sciences, Inc. , a leading provider of unique flexible endoscopic products utilizing its proprietary sterile disposable EndoSheath® technology, today reported

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Vision-Sciences Reports Record Third Quarter Fiscal 2012 Net Sales of $4.3 Million

Science Shows How Exercise Might Help in Prostate Cancer

TUESDAY, Jan. 31 (HealthDay News) — Vigorous exercise causes changes in some 180 prostate genes among men with early stage prostate cancer, a new study suggests.

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Science Shows How Exercise Might Help in Prostate Cancer

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